Traf4 CLIA Kit for Mouse(Mus musculus) | EIAab.comTraf4 CLIA Kit for Mouse(Mus musculus)

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Traf4 (Gene name),

TNF receptor-associated factor 4 (Protein name ), TRAF4_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Traf4(Cart1);

Protein name:

TNF receptor-associated factor 4;

Alternative:

Cysteine-rich motif associated to RING and Traf domains protein 1;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homotrimer (Probable). Interacts with LTBR/TNFRSF3, NGFR/TNFRSF16, RPS6KB1 and TGFB1I1. Interacts with SMURF1. Interacts (via TRAF domain) with MAP3K4 (via kinase domain). Interacts with NCF1, TICAM1, IRAK1 and TRAF6, and is probably part of a complex containing TRAF4, NCF1, TICAM1, IRAK1 and TRAF6.

Function:

Adapter protein and signal transducer that links members of the tumor necrosis factor receptor (TNFR) family to different signaling pathways. Plays a role in the activation of NF-kappa-B and JNK, and in the regulation of cell survival and apoptosis. Regulates activation of NF-kappa-B in response to signaling through Toll-like receptors. Required for activation of RPS6KB1 in response to TNF signaling. Modulates TRAF6 functions (By similarity). Required for normal skeleton development, and for normal development of the respiratory tract.

Subcellular Location:

Cytoplasm Nucleus Cytoplasm perinuclear region Cell junction tight junction Cell membrane Peripheral membrane protein Cytoplasmic side Cytoplasm cytoskeleton

Protein Attributes:

Sequence length:

470

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

470:

VRDDAVFIRA | SVELPRKILS |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

mmu:22032

SMR:

Q61382

STRING:

10090.ENSMUSP00000017530

String:

Q61382

UniGene:

Mm.390418

Pfam:

PF00917

Uniprot:

Q61382

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ELISA Kit for Mouse TNF receptor-associated factor 4

Cat.:

E15310h

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Packing:

96T

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ELISA Kit for Mouse TNF receptor-associated factor 4

Cat.:

E15310m

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MSDS:

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Packing:

96T

CLIA Kit for Mouse TNF receptor-associated factor 4

Cat.:

U15310h

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MSDS:

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Packing:

96T

CLIA Kit for Mouse TNF receptor-associated factor 4

Cat.:

U15310m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse TNF receptor-associated factor 4

Cat.:

P15310Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse TNF receptor-associated factor 4

Cat.:

P15310Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse TNF receptor-associated factor 4

Protein for Mouse TNF receptor-associated factor 4

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Tumor necrosis factor receptor associated factor 4 (TRAF4) expression pattern during mouse development."
Masson R. , Regnier C.H. , Chenard M.-P. , Wendling C. , Mattei M.-G. , Tomasetto C. , Rio M.-C.
Mech. Dev.71:187-191(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
tissue: Embryonic stem cell.
2.

"Complete structural characterisation of the mammalian and Drosophila TRAF genes: implications for TRAF evolution and the role of RING finger splice variants."
Grech A. , Quinn R. , Srinivasan D. , Badoux X. , Brink R.
Mol. Immunol.37:721-734(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: C57BL/6.
tissue: Fetus.
tissue: Spleen.
3.

"The transcriptional landscape of the mammalian genome."
Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C57BL/6J.
tissue: Aorta.
tissue: Embryo.
tissue: Eye.
tissue: Vein.
4.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
5.

Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"TRAF4 deficiency leads to tracheal malformation with resulting alterations in air flow to the lungs."
Shiels H. , Li X. , Schumacker P.T. , Maltepe E. , Padrid P.A. , Sperling A. , Thompson C.B. , Lindsten T.
Am. J. Pathol.157:679-688(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: POTENTIAL FUNCTION;DISRUPTION PHENOTYPE
7.

"Impaired neural tube closure, axial skeleton malformations, and tracheal ring disruption in TRAF4-deficient mice."
Regnier C.H. , Masson R. , Kedinger V. , Textoris J. , Stoll I. , Chenard M.P. , Dierich A. , Tomasetto C. , Rio M.C.
Proc. Natl. Acad. Sci. U.S.A.99:5585-5590(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
8.

"MEKK4 is an effector of the embryonic TRAF4 for JNK activation."
Abell A.N. , Johnson G.L.
J. Biol. Chem.280:35793-35796(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MAP3K4
9.

"Characterization of immune functions in TRAF4-deficient mice."
Cherfils-Vicini J. , Vingert B. , Varin A. , Tartour E. , Fridman W.H. , Sautes-Fridman C. , Regnier C.H. , Cremer I.
Immunology124:562-574(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE

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